Knowing All About Vitamin B5 Pantothenic
Pantothenic acid is also called as Vitamin B5 and it is soluble in water. It is considered
as an essential nutrient required for sustaining the life. Pantothenic acid is required for the formation of
coenzyme-A (CoA) and it is evaluated critical in the metabolism, production of carbohydrates, fats and proteins.
The chemical structure of Pantothenic acid is amide between D-pantoate and beta-alanine. This name was derived from
the Greek pantothen which provides the meaning “from everywhere” and the small quantities of Pantothenic acid are
found active in all the food items. Pantothenic acid is richly present in whole-grain cereals, eggs, legumes, royal
jelly and meat.
This acid is commonly found in the alcohol analog, calcium pantotherate and provitamin panthenaol. The
dextrorotatory (D) isomer of Pantothenic acid requires biologic activity and the levoratatory (L) form may
antagonize the effects of the dextrorotatory isomer.
Pantothenic acid is used in the production of coenzyme A and it acts as an acyl group carrier to form acetyl-CoA
and other similar composites. This act involves the transportation of atom inside the cell. The transformation of
the carbon atoms by the coenzyme A is an important process in the cellular respiration and bioproduction of may
essential compounds like fatty acids, cholesterol and acetylcholine.
Pantothenic acid is considered as an essential element is all forms of life because of the participation in the
wide array of biological roles. Pantothenic acid has existence of various numbers of deficiencies. This acid is
considered important for a healthy pregnancy. Pantothenic acid is found in small quantities in most of the food and
it is found in high quantities like whole grain and eggs. Existence of Pantothenic acid in the dietary supplements
as calcium D-pantotherate and some companies are adding this acid in the beverages. Recent studies have revealed
that the gut bacteria present in the body of human can generate Pantothenic acid.
Pantothenate in the form of pantethine is said to be more energetic form of the vitamin in the body and it
remains unstable at high temperature or storage for longer periods. Hence calcium Pantothenate is the usual form of
vitamin B5 and it is sold as a dietary supplement. Proportion of 10mg of calcium panthothenate is equal to 9.2mg of
Pantothenic acid. Studies have revealed that the deficiency of Pantothenic acid is exclusively uncommon. Symptoms
like starvation and limited volunteer trials are determined to be the deficiency of Pantothenic acid. These
deficiencies are related to the deficiencies of vitamin B. Minor deficiencies like allergies, fatigue, and
abdominal pain prevail due to lack of Pantothenic acid. Major conditions like adrenal insufficiency and hepatic
encephalopathy arise due to the deficiency in Pantothenic acid.
Abnormal sensations in the soles of the feet were reported as a common deficiency arising due to Pantothenic
acid. Studies have revealed that 28 out of 33 patients when treated with alpha-lipoic acid for peripheral
polyneuropathy have reported improvement with the combination of Pantothenic acid. Clinical studies have revealed
that diabetic neuropathy prevails due to the existence of latent prediabetic metabolic disturbances and the usage
of Pantothenic acid helps in the cure of the disease.